European training network for development of personalized anti-infective medical devices combining printing technologies and antimicrobial functionality

The objective of WP3 is to demonstrate the in vivo antimicrobial activity of the 3D-printed devices and formulations developed in WPs 1 and 2. The best candidates will be selected based upon the results of the in vitro functionality tests described in WP2 earlier. Animal models remain indispensable to provide a more predictive outcome on the efficacy of antimicrobials. Although some models have been previously described, determining the optimal infection and monitoring conditions remain challenging, as no standard models are available.